Three patients with middle-age-onset hemochromatosis caused by novel mutations in the hemojuvelin gene.

@article{Koyama2005ThreePW,
  title={Three patients with middle-age-onset hemochromatosis caused by novel mutations in the hemojuvelin gene.},
  author={Chizu Koyama and Hisao Hayashi and Shinya Wakusawa and Toshio Ueno and Motoyoshi Yano and Yoshiaki Katano and Hidemi Goto and Ryuichi Kidokoro},
  journal={Journal of hepatology},
  year={2005},
  volume={43 4},
  pages={740-2}
}
Hemochromatosis is a genetically heterogeneous condition. Mutations in the recently described hemojuvelin gene were found in patients with juvenile hemochromatosis, who usually manifest clinical signs of iron overload, including cardiomyopathy and hypogonadism, in their teens and early 20s. In this report, we describe three Japanese patients who showed… CONTINUE READING