Three new macrolide efflux (mef) gene variants in Streptococcus agalactiae.

@article{Cai2007ThreeNM,
  title={Three new macrolide efflux (mef) gene variants in Streptococcus agalactiae.},
  author={Yongwei Cai and Fanrong Kong and Gwendolyn L. Gilbert},
  journal={Journal of clinical microbiology},
  year={2007},
  volume={45 8},
  pages={2754-5}
}
Streptococcus agalactiae (group B streptococcus [GBS]) is the most common cause of neonatal sepsis (9). Penicillin is used for intrapartum prophylaxis, but erythromycin or clindamycin is recommended for patients allergic to penicillin (3). There are two major mechanisms of erythromycin resistance in S. agalactiae, (i) erythromycin ribosomal methylase, mediated by ermB, ermA, ermTR, or ermC, which confers cross-resistance to macrolides, lincosamides, and streptogramin B (MLSB phenotype), and (ii… CONTINUE READING
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