Three muscular dystrophies: Loss of cytoskeleton-extracellular matrix linkage

@article{Campbell1995ThreeMD,
  title={Three muscular dystrophies: Loss of cytoskeleton-extracellular matrix linkage},
  author={Kevin P Campbell},
  journal={Cell},
  year={1995},
  volume={80},
  pages={675-679}
}
Muscular dystrophies are a group of diseases that primarily affect skeletal muscle and are characterized by progressive muscle wasting and weakness. Although these diseases have been clinically recognized for a number of years, genetic defects in a number of muscular dystrophies have only recently been identified. One of the most important advances in understanding the molecular genetics of neuromuscular diseases has been the cloning of the gene encoding dystrophin, the protein absent in muscle… CONTINUE READING

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