Three-in-one nerve block with different concentrations of bupivacaine in total knee arthroplasty: randomized, placebo-controlled, double-blind trial.

@article{Xie2012ThreeinoneNB,
  title={Three-in-one nerve block with different concentrations of bupivacaine in total knee arthroplasty: randomized, placebo-controlled, double-blind trial.},
  author={Zheng Xie and Waqas Hussain and Thomas W Cutter and Jeffrey L. Apfelbaum and Melinda L. Drum and David Worland Karen Manning},
  journal={The Journal of arthroplasty},
  year={2012},
  volume={27 5},
  pages={673-8.e1}
}
Pain after total knee arthroplasty may be severe and lead to adverse outcomes. Using 2 concentrations of bupivacaine, we investigated 3-in-1 nerve block's effect on pain control, narcotic use, sedation, and patient satisfaction. One hundred five patients undergoing unilateral total knee arthroplasty were randomized into 3 groups: low-dose or high-dose bupivacaine or placebo. Ninety-nine patients completed the study. Three-in-1 nerve block reduced patient-controlled opioid analgesia usage and… CONTINUE READING