Three-generation evaluation of Y-chromosome microdeletion.

  title={Three-generation evaluation of Y-chromosome microdeletion.},
  author={Sandra E Kleiman and Leah Yogev and Ronni Gamzu and Ron Hauser and Amnon Botchan and Gedalia F. Paz and Joseph B. Lessing and Yuval Yaron and Haim Yavetz},
  journal={Journal of andrology},
  volume={20 3},
Sperm cells can be retrieved directly from the testis (testicular sperm extraction [TESE] procedure) and used for intracytoplasmic sperm injection (ICSI), circumventing underlying spermatogenetic defects. Thus, it is important that added information be available on the genetic defects in men undergoing TESE for the ICSI procedure and on the transmission of genetic factors associated with infertility to the offspring. We report a three-generation genetic analysis of a family with a case of male… CONTINUE READING
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