Three distinguishable phenotypes in golden retriever muscular dystrophy

  title={Three distinguishable phenotypes in golden retriever muscular dystrophy},
  author={Carlos E Ambr{\'o}sio and Leandro Fadel and Tha{\'i}s P. Gaiad and Dayane S Martins and Karla Patr{\'i}cia Cardoso Ara{\'u}jo and Eder Zucconi and Marina Pandolphi Br{\'o}lio and Robson Fortes Giglio and Adriana Caroprezo Morini and Tatiana Jazedje and Tilde Rodrigues Froes and Matheus Levi Tajra Feitosa and Marcos Costa Valadares and Patricia Cristina Baleeiro Beltr{\~a}o-Braga and Fl{\'a}vio Vieira Meirelles and M. A. Miglino},
  journal={Neuromuscular Disorders},
Duchenne muscular dystrophy (DMD) is a human disease characterized by progressive and irreversible skeletal muscle degeneration caused by mutations in genes coding for important muscle proteins. Unfortunately, there is no efficient treatment for this disease; it causes progressive loss of motor and muscular ability until death. The canine model (golden retriever muscular dystrophy) is similar to DMD, showing similar clinical signs. Fifteen dogs were followed from birth and closely observed for… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 19 extracted citations

Adaptive Immune Response Impairs the Efficacy of Autologous Transplantation of Engineered Stem Cells in Dystrophic Dogs.

Molecular therapy : the journal of the American Society of Gene Therapy • 2016
View 3 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 39 references

Gene therapy in Duchenne muscular dystrophy

Brain and Development • 1996
View 4 Excerpts
Highly Influenced

Abdominal and pelvic ultrasonography

Neuromuscul. Disord

Abdominal and pelvic ultrasonography in healthy golden retriever dogs , carriers and affected by gradual muscular dystrophy . Cienc

AP Grando, Mariana ANB, MA Miglino, FA Sterman
Rural • 2009
View 1 Excerpt

Radiologic images of the thoracic cavity of Golden Retriever dogs

FR Alves, MLT Feitosa, A Gatti, L Fadel
View 1 Excerpt

Radiologic images of the thoracic cavity of Golden Retriever dogs affected by muscular dystrophy

FR Alves, Feitosa MLT, A Gatti, L Fadel
Pesq . Vet . Bras • 2009
View 1 Excerpt

death to asymptomatic carriers. Neuromuscul

CE Ambrosio, MC Valadares, E Zucconi, R Cabral
View 3 Excerpts

Animal Models for Genetic Neuromuscular Diseases

Journal of Molecular Neuroscience • 2007
View 1 Excerpt

Similar Papers

Loading similar papers…