Three-dimensional structure of the toxin-delivery particle antifeeding prophage of Serratia entomophila.

@article{Heymann2013ThreedimensionalSO,
  title={Three-dimensional structure of the toxin-delivery particle antifeeding prophage of Serratia entomophila.},
  author={J Bernard Heymann and Joseph D Bartho and Daria Rybakova and Hari P Venugopal and Dennis C. Winkler and Anindito Sen and Mark Robin Holmes Hurst and Alok K Mitra},
  journal={The Journal of biological chemistry},
  year={2013},
  volume={288 35},
  pages={25276-84}
}
The Serratia entomophila antifeeding prophage (Afp) is a bullet-shaped toxin-delivery apparatus similar to the R-pyocins of Pseudomonas aeruginosa. Morphologically it resembles the sheathed tail of bacteriophages such as T4, including a baseplate at one end. It also shares features with the type VI secretion systems. Cryo-electron micrographs of tilted Afp specimens (up to 60 degrees) were analyzed to determine the correct cyclic symmetry to overcome the limitation imposed by exclusively side… CONTINUE READING
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