Three dimensional structure of the soybean agglutinin Gal/GalNAc complexes by homology modeling.

@article{Rao1998ThreeDS,
  title={Three dimensional structure of the soybean agglutinin Gal/GalNAc complexes by homology modeling.},
  author={Vatluri Srinivasa Rao and K Lam and Pradman K. Qasba},
  journal={Journal of biomolecular structure & dynamics},
  year={1998},
  volume={15 5},
  pages={853-60}
}
Complexes of soybean agglutinin (SBA) with galactose (Gal) and N-acetyl galactosamine (GalNAc) have been modeled based on its homology to erythrina corallodendron (EcorL) lectin. The three dimensional structure of SBA-Gal modeled with homology techniques agrees well with SBA-(beta-LacNAc)2Gal-R complex determined by X-ray crystallographic techniques at the beta-sheet regions and the regions where Ca2+ and Mn2+ ions bind. However, significant deviations have been observed between the modeled and… CONTINUE READING