Three dimensional structure of the seventh transmembrane helical domain of the G-protein receptor, rhodopsin.

@article{Yeagle2000ThreeDS,
  title={Three dimensional structure of the seventh transmembrane helical domain of the G-protein receptor, rhodopsin.},
  author={Philip L. Yeagle and Carole Danis and Gregory Choi and James L. Alderfer and Arlene D. Albert},
  journal={Molecular vision},
  year={2000},
  volume={6},
  pages={
          125-31
        }
}
PURPOSE The three dimensional structure of a peptide comprising the sequence of the seventh transmembrane segment of the G-protein coupled receptor, rhodopsin, was determined in solution. METHODS The sequence of the seventh transmembrane segment of rhodopsin, which contains the NPxxY sequence that is highly conserved among G-protein coupled receptors and lys296 that forms the Schiff base with the retinal, was synthesized by solid phase peptide synthesis. The three dimensional structure was… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Similar Papers

Loading similar papers…