Three-dimensional structure of the adenovirus major coat protein hexon.

  title={Three-dimensional structure of the adenovirus major coat protein hexon.},
  author={Marion M Roberts and Janice L. White and Markus G. Gruetter and Roger M. Burnett},
  volume={232 4754},
The three-dimensional crystal structure of the adenovirus major coat protein is presented. Adenovirus type 2 hexon, at 967 residues, is now the longest polypeptide whose structure has been determined crystallographically. Taken with our model for hexon packing, which positions the 240 trimeric hexons in the capsid, the structure defines 60% of the protein within the 150 X 10(6) dalton virion. The assembly provides the first details of a DNA-containing animal virus that is 20 times larger than… CONTINUE READING

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