Three-dimensional structure of the RGD-containing neurotoxin homologue dendroaspin


Dendroaspin is a short chain neurotoxin homologue from the venom of Elapidae snakes, which lacks neurotoxicity. Unlike neurotoxins, it contains an Arg-Gly-Asp-(RGD)-motif and functions as an inhibitor of platelet aggregation and platelet adhesion with comparable potency to the disintegrins from the venoms of Viperidae. We have determined the structure of… (More)
DOI: 10.1038/nsb1194-802


  • Presentations referencing similar topics