Three-dimensional structure of infectious bursal disease virus determined by electron cryomicroscopy.

@article{Bttcher1997ThreedimensionalSO,
  title={Three-dimensional structure of infectious bursal disease virus determined by electron cryomicroscopy.},
  author={B. B{\"o}ttcher and N. Kiselev and V. Y. Stel'mashchuk and N. Perevozchikova and A. Borisov and R. Crowther},
  journal={Journal of virology},
  year={1997},
  volume={71 1},
  pages={
          325-30
        }
}
Infectious bursal disease virus (IBDV), a member of the Birnaviridae group, is a commercially important pathogen of chickens. From electron micrographs of frozen, hydrated, unstained specimens, we have computed a three-dimensional map of IBDV at about 2 nm resolution. The map shows that the structure of the virus is based on a T=13 lattice and that the subunits are predominantly trimer clustered. The subunits close to the fivefold symmetry axes are at a larger radius than those close to the two… Expand
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