Three-dimensional structure of a hammerhead ribozyme

@article{Pley1994ThreedimensionalSO,
  title={Three-dimensional structure of a hammerhead ribozyme},
  author={Heinz W. Pley and Kevin M. Flaherty and David B. Mckay},
  journal={Nature},
  year={1994},
  volume={372},
  pages={68-74}
}
The hammerhead ribozyme is a small catalytic RNA motif made up of three base-paired stems and a core of highly conserved, non-complementary nucleotides essential for catalysis. The X-ray crystallographic structure of a hammerhead RNA–DNA ribozyme-inhibitor complex at 2.6 Å resolution reveals that the base-paired stems are A-form helices and that the core has two structural domains. The first domain is formed by the sequence 5′-CUGA following stem I and is a sharp turn identical to the uridine… 
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Probing the Cleavage Activity of the Hammerhead Ribozyme Using Analog Complexes
TLDR
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TLDR
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TLDR
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