Three-dimensional structure of baculovirus-expressed Norwalk virus capsids.

  title={Three-dimensional structure of baculovirus-expressed Norwalk virus capsids.},
  author={B. V. Venkataram Prasad and Rosalba Rothnagel and Xiaoqun Jiang and Mary K. Estes},
  journal={Journal of virology},
  volume={68 8},
The three-dimensional structure of the baculovirus-expressed Norwalk virus capsid has been determined to a resolution of 2.2 nm using electron cryomicroscopy and computer image processing techniques. The empty capsid, 38.0 nm in diameter, exhibits T = 3 icosahedral symmetry and is composed of 90 dimers of the capsid protein. The striking features of the capsid structure are arch-like capsomeres, at the local and strict 2-fold axes, formed by dimers of the capsid protein and large hollows at the… CONTINUE READING


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