Three-dimensional structural analysis of tetanus toxin by electron crystallography.

  title={Three-dimensional structural analysis of tetanus toxin by electron crystallography.},
  author={John P. Robinson and Michael F. Schmid and Daniel G. Morgan and Wah Chiu},
  journal={Journal of molecular biology},
  volume={200 2},
Two-dimensional crystalline arrays of native tetanus toxin have been formed at the interface between a solution of the toxin and a phospholipid monolayer containing a ganglioside. Electron crystallographic analysis has been used to study these periodic arrays. The arrays obey the symmetry of plane group p12(1), with a = 126 A and b = 84 A, and a thickness of 90 A (1 A = 0.1 nm). The three-dimensional structure of tetanus toxin in negative stain is reconstructed to a nominal resolution of 14 A… CONTINUE READING

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