Three-dimensional relationships between tumor cells and microcirculation with double cyanine immunolabeling, laser scanning confocal microscopy, and computer-assisted reconstruction: an alternative to cast corrosion preparations.

@article{Rummelt1994ThreedimensionalRB,
  title={Three-dimensional relationships between tumor cells and microcirculation with double cyanine immunolabeling, laser scanning confocal microscopy, and computer-assisted reconstruction: an alternative to cast corrosion preparations.},
  author={Volker Rummelt and Lynn M. G. Gardner and Robert Folberg and Samuel Beck and Boyd M. Knosp and Thomas O. Moninger and Kenneth Charles Moore},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1994},
  volume={42 5},
  pages={681-6}
}
The morphology of the microcirculation of uveal melanomas is a reliable market of tumor progression. Scanning electron microscopy of cast corrosion preparations can generate three-dimensional views of these vascular patterns, but this technique sacrifices the tumor parenchyma. Formalin-fixed wet tissue sections 100-150 microns thick from uveal melanomas… CONTINUE READING