Three-dimensional reconstruction of single particles from random and nonrandom tilt series.

@article{Radermacher1988ThreedimensionalRO,
  title={Three-dimensional reconstruction of single particles from random and nonrandom tilt series.},
  author={Michael Radermacher},
  journal={Journal of electron microscopy technique},
  year={1988},
  volume={9 4},
  pages={359-94}
}
To overcome the radiation damage-induced limitations to the resolution of three-dimensional reconstructions from electron microscopic tilt series, novel reconstruction schemes have been developed that require only a single exposure of the specimen. The tilt series collected with these methods have random projection directions. First, three-dimensional reconstruction techniques are described that are applicable to data obtained from tilt series with regular tilt geometry, followed by the… CONTINUE READING
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