Three-dimensional reconstruction of extravascular matrix patterns and blood vessels in human uveal melanoma tissue: techniques and preliminary findings.

@article{Chen2003ThreedimensionalRO,
  title={Three-dimensional reconstruction of extravascular matrix patterns and blood vessels in human uveal melanoma tissue: techniques and preliminary findings.},
  author={Xue Chen and Zhuming Ai and Mary Rasmussen and Peter Bajcsy and Loretta Auvil and Michael Welge and Lu Leach and Sumalee Vangveeravong and Andrew J. Maniotis and Robert Folberg},
  journal={Investigative ophthalmology & visual science},
  year={2003},
  volume={44 7},
  pages={2834-40}
}
PURPOSE Looping patterns rich in laminin are present in tissue samples of primary aggressive human uveal melanomas and their metastases. Because these extravascular patterns connect to blood vessels and transmit fluid in vitro and in vivo, the three-dimensional configuration of these patterns has been the subject of considerable speculation. In the current study, methods were devised to describe the three-dimensional configuration of looping extravascular matrix patterns in archival human uveal… CONTINUE READING

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