Three-dimensional reconstruction of dynamin in the constricted state

  title={Three-dimensional reconstruction of dynamin in the constricted state},
  author={Peijun Zhang and Jenny E. Hinshaw},
  journal={Nature Cell Biology},
Members of the dynamin family of GTPases have unique structural properties that might reveal a general mechanochemical basis for membrane constriction. Receptor-mediated endocytosis, caveolae internalization and certain trafficking events in the Golgi all require dynamin for vesiculation. The dynamin-related protein Drp1 (Dlp1) has been implicated in mitochondria fission and a plant dynamin-like protein phragmoplastin is involved in the vesicular events leading to cell wall formation. A common… CONTINUE READING
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