Three-dimensional reconstruction of Heterocapsa circularisquama RNA virus by electron cryo-microscopy.

@article{Miller2011ThreedimensionalRO,
  title={Three-dimensional reconstruction of Heterocapsa circularisquama RNA virus by electron cryo-microscopy.},
  author={Jennifer M. Miller and Jeremy Woodward and Shaoxia Chen and Mohammed Jaffer and Brandon Weber and Keizo Nagasaki and Yuji Tomaru and Roger Wepf and Alan M. Roseman and Arvind Varsani and Trevor Sewell},
  journal={The Journal of general virology},
  year={2011},
  volume={92 Pt 8},
  pages={1960-70}
}
Heterocapsa circularisquama RNA virus is a non-enveloped icosahedral ssRNA virus infectious to the harmful bloom-forming dinoflagellate, H. circularisquama, and which is assumed to be the major natural agent controlling the host population. The viral capsid is constructed from a single gene product. Electron cryo-microscopy revealed that the virus has a diameter of 34 nm and T = 3 symmetry. The 180 quasi-equivalent monomers have an unusual arrangement in that each monomer contributes to a 'bump… CONTINUE READING

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