Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering.

@article{Seitz2005ThreedimensionalPO,
  title={Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering.},
  author={Hermann Seitz and Wolfgang Rieder and Stephan H. Irsen and Barbara Leukers and Carsten Tille},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  year={2005},
  volume={74 2},
  pages={
          782-8
        }
}
  • H. Seitz, Wolfgang Rieder, +2 authors C. Tille
  • Published 2005
  • Medicine, Materials Science
  • Journal of biomedical materials research. Part B, Applied biomaterials
This article reports a new process chain for custom-made three-dimensional (3D) porous ceramic scaffolds for bone replacement with fully interconnected channel network for the repair of osseous defects from trauma or disease. Rapid prototyping and especially 3D printing is well suited to generate complex-shaped porous ceramic matrices directly from powder materials. Anatomical information obtained from a patient can be used to design the implant for a target defect. In the 3D printing technique… Expand
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References

SHOWING 1-10 OF 23 REFERENCES
Three-dimensional printing and porous metallic surfaces: a new orthopedic application.
TLDR
It is postulated that an increased volume of ingrown bone, resulting from a combination of high surface porosity and a high percentage of ingrowth, was responsible for the observed improvement in strength. Expand
Performance of hydroxyapatite bone repair scaffolds created via three-dimensional fabrication techniques.
TLDR
It is indicated that scaffold geometry, as determined by the fabrication process, can enhance the ability of a ceramic material to accelerate healing of calvarial defects. Expand
Performance of degradable composite bone repair products made via three-dimensional fabrication techniques.
TLDR
This proof-of-concept study demonstrated that channel size, porosity, and pore size can be controlled and used to influence new bone formation and calvarial defect healing. Expand
Design and fabrication of standardized hydroxyapatite scaffolds with a defined macro-architecture by rapid prototyping for bone-tissue-engineering research.
This investigation describes the production and characterization of calcium phosphate scaffolds with defined and reproducible porous macro-architectures and their preliminary in vitro and in vivo… Expand
Hydroxyapatite implants with designed internal architecture
TLDR
The results show that HA implants with designed connection pattern and well controled channel size can be built with the technique developed in this study. Expand
Indirect solid free form fabrication of local and global porous, biomimetic and composite 3D polymer-ceramic scaffolds.
Precise control over scaffold material, porosity, and internal pore architecture is essential for tissue engineering. By coupling solid free form (SFF) manufacturing with conventional sponge scaffold… Expand
Scaffold development using 3D printing with a starch-based polymer
Rapid prototyping (RP) techniques have been utilised by tissue engineers to produce three-dimensional (3D) porous scaffolds. RP technologies allow the design and fabrication of complex scaffold… Expand
Fabrication of 3D chitosan–hydroxyapatite scaffolds using a robotic dispensing system
Abstract A new robotic desktop rapid prototyping (RP) system was designed to fabricate scaffolds for tissue engineering applications. The experimental setup consists of a computer-guided desktop… Expand
Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling.
TLDR
FDM allows the design and fabrication of highly reproducible bioresorbable 3D scaffolds with a fully interconnected pore network and shows that fibroblasts and osteoblast-like cells can proliferate, differentiate, and produce a cellular tissue in an entirely interconnected 3D polycaprolactone matrix. Expand
Hydroxyapatite cement scaffolds with controlled macroporosity: fabrication protocol and mechanical properties.
Precipitated hydroxyapatite cement scaffolds with macroporosity of controlled size and shape were successfully built using a solid freeform fabrication process. The negative macroporosity was… Expand
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