Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering.
@article{Seitz2005ThreedimensionalPO, title={Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering.}, author={Hermann Seitz and Wolfgang Rieder and Stephan H. Irsen and Barbara Leukers and Carsten Tille}, journal={Journal of biomedical materials research. Part B, Applied biomaterials}, year={2005}, volume={74 2}, pages={ 782-8 } }
This article reports a new process chain for custom-made three-dimensional (3D) porous ceramic scaffolds for bone replacement with fully interconnected channel network for the repair of osseous defects from trauma or disease. Rapid prototyping and especially 3D printing is well suited to generate complex-shaped porous ceramic matrices directly from powder materials. Anatomical information obtained from a patient can be used to design the implant for a target defect. In the 3D printing technique…
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References
SHOWING 1-10 OF 21 REFERENCES
Three-dimensional printing and porous metallic surfaces: a new orthopedic application.
- Materials ScienceJournal of biomedical materials research
- 2001
It is postulated that an increased volume of ingrown bone, resulting from a combination of high surface porosity and a high percentage of ingrowth, was responsible for the observed improvement in strength.
Performance of hydroxyapatite bone repair scaffolds created via three-dimensional fabrication techniques.
- Materials ScienceJournal of biomedical materials research. Part A
- 2003
It is indicated that scaffold geometry, as determined by the fabrication process, can enhance the ability of a ceramic material to accelerate healing of calvarial defects.
Performance of degradable composite bone repair products made via three-dimensional fabrication techniques.
- Materials Science, EngineeringJournal of biomedical materials research. Part A
- 2003
This proof-of-concept study demonstrated that channel size, porosity, and pore size can be controlled and used to influence new bone formation and calvarial defect healing.
Design and fabrication of standardized hydroxyapatite scaffolds with a defined macro-architecture by rapid prototyping for bone-tissue-engineering research.
- Materials Science, MedicineJournal of biomedical materials research. Part A
- 2004
This investigation describes the production and characterization of calcium phosphate scaffolds with defined and reproducible porous macro-architectures and their preliminary in vitro and in vivo…
Hydroxyapatite implants with designed internal architecture
- Materials ScienceJournal of materials science. Materials in medicine
- 2001
The results show that HA implants with designed connection pattern and well controled channel size can be built with the technique developed in this study.
Indirect solid free form fabrication of local and global porous, biomimetic and composite 3D polymer-ceramic scaffolds.
- Materials Science, EngineeringBiomaterials
- 2003
Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling.
- Biology, Materials ScienceJournal of biomedical materials research
- 2001
FDM allows the design and fabrication of highly reproducible bioresorbable 3D scaffolds with a fully interconnected pore network and shows that fibroblasts and osteoblast-like cells can proliferate, differentiate, and produce a cellular tissue in an entirely interconnected 3D polycaprolactone matrix.
Hydroxyapatite cement scaffolds with controlled macroporosity: fabrication protocol and mechanical properties.
- Materials ScienceBiomaterials
- 2003
Use of stereolithography to manufacture critical-sized 3D biodegradable scaffolds for bone ingrowth.
- Materials ScienceJournal of biomedical materials research. Part B, Applied biomaterials
- 2003
A novel approach to the manufacture of biodegradable polymeric scaffolds for tissue-engineering utilizing stereolithography (SLA) is presented, which has application in the tissue engineering of bony substrates.