Three-dimensional printing for drug delivery devices: a state-of-the-art survey

  title={Three-dimensional printing for drug delivery devices: a state-of-the-art survey},
  author={Almog Uziel and Tal Shpigel and Nir Goldin and Dan Y. Lewitus},
  journal={Journal of 3D Printing in Medicine},
Over the last several decades, 3D printing technology, which encompasses many different fabrication techniques, had emerged as a promising tool in many fields of production, including the pharmaceutical industry. Specifically, 3D printing may be advantageous for drug delivery systems, systems aiming to improve the pharmacokinetics of drugs. These advantages include the ease of designing complex shapes, printing of drugs on demand, tailoring dosage to the specific needs of the patient and… 
2 Citations
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ABSTRACT The potential of fused filament fabrication (FFF) for the administration of active pharmaceutical compounds is a recent approach to develop complex and custom-made drug delivery systems
Nanocarrier-hydrogel composite delivery systems for precision drug release.
  • Lauren E. Kass, J. Nguyen
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    Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
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This review discusses two main important advances in hydrogel fabrication for precision drug release: first, the incorporation of nanocarriers to diversify their drug loading capability, and second, the design of hydrogels using 3D printing to precisely control drug dosing and release kinetics via high-resolution structures and geometries.


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The 3D printing technologies being utilized for the fabrication of drug delivery systems, as well as the formulation and processing parameters for consideration, are highlighted and the range of dosage forms prepared using these technologies, specifically over the last 10 years are summarized.
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This review summarizes the newest achievements and challenges of additive manufacturing in the field of pharmaceutical and biomedical research that have been published since 2015.
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Emergence of 3D Printed Dosage Forms: Opportunities and Challenges
Various3D printing technologies such as stereolithographic, powder based, selective laser sintering, fused deposition modelling and semi-solid extrusion 3D printing are presented and their advantages particularly with adaptability in the pharmaceutical field have been highlighted.
Identification of Novel "Inks" for 3D Printing Using High-Throughput Screening: Bioresorbable Photocurable Polymers for Controlled Drug Delivery.
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Fabrication of drug-loaded hydrogels with stereolithographic 3D printing.