Three-dimensional organization of the collagen fibrillar framework of the human and rat livers.

  • Osamu Ohtani
  • Published 1988 in Archives of histology and cytology


The collagen fibrillar framework in the human and rat liver was demonstrated by a cell-maceration/scanning electron microscope (SEM) method. Maceration of fixed tissues with alkali plus water successfully removed the cellular elements, exposing collagen fibrils which measured about 60 nm in diameter and were identified as such by transmission electron… (More)