Three-dimensional nanohydroxyapatite/chitosan scaffolds as potential tissue engineered periodontal tissue.

@article{Zhang2007ThreedimensionalNS,
  title={Three-dimensional nanohydroxyapatite/chitosan scaffolds as potential tissue engineered periodontal tissue.},
  author={Yu-feng Zhang and Xiang-rong Cheng and Yun Chen and Bin Shi and Xiaohui Chen and Dong-xuan Xu and Jin Chi Ke},
  journal={Journal of biomaterials applications},
  year={2007},
  volume={21 4},
  pages={333-49}
}
The development of suitable three-dimensional scaffold for the maintenance of cellular viability and differentiation is critical for applications in periodontal tissue engineering. In this work, different ratios of porous nanohydroxyapatite/chitosan (HA/chitosan) scaffolds are prepared through a freeze-drying process. These scaffolds are evaluated in vitro by the analysis of microscopic structure, porosity, and cytocompatibility. The expression of type I collagen and alkaline phosphatase (ALP… CONTINUE READING

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