We extend the diffuse interface model developed in Wise et al. (2008) to study nonlinear tumor growth in 3-D. Extensions include the tracking of multiple viable cell species populations through a continuum diffuse-interface method, onset and aging of discrete tumor vessels through angiogenesis, and incorporation of individual cell movement using a hybrid… (More)

@article{Frieboes2010ThreedimensionalMN,
title={Three-dimensional multispecies nonlinear tumor growth-II: Tumor invasion and angiogenesis.},
author={Hermann B. Frieboes and Fang Jin and Yao-Li Chuang and Steven M. Wise and John S. Lowengrub and Vittorio Cristini},
journal={Journal of theoretical biology},
year={2010},
volume={264 4},
pages={1254-78}
}