Three-dimensional localization of the smallest capsid protein in the human cytomegalovirus capsid.

@article{Yu2005ThreedimensionalLO,
  title={Three-dimensional localization of the smallest capsid protein in the human cytomegalovirus capsid.},
  author={Xuekui Yu and Sanket U Shah and Ivo Atanasov and Pierrette Lo and Fenyong Liu and William J Britt and Z. Hong Zhou},
  journal={Journal of virology},
  year={2005},
  volume={79 2},
  pages={1327-32}
}
The smallest capsid proteins (SCPs) of the human herpesviruses differ substantially in size and sequence and are thought to impart some unique aspects of infection to their respective viruses. We used electron cryomicroscopy and antibody labeling to show that the 8-kDa SCP of human cytomegalovirus is attached only to major capsid protein subunits of the hexons, not the pentons. Thus, the SCPs of different herpesviruses illustrate that a protein can evolve significantly in sequence, structure… CONTINUE READING

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