Three-dimensional epithelial tissues generated from human embryonic stem cells.

@article{Hewitt2009ThreedimensionalET,
  title={Three-dimensional epithelial tissues generated from human embryonic stem cells.},
  author={Kyle J. Hewitt and Yulia Shamis and Mark W. Carlson and Edith Aberdam and Daniel Aberdam and Jonathan A. Garlick},
  journal={Tissue engineering. Part A},
  year={2009},
  volume={15 11},
  pages={3417-26}
}
The use of pluripotent human embryonic stem (hES) cells for tissue engineering may provide advantages over traditional sources of progenitor cells because of their ability to give rise to multiple cell types and their unlimited expansion potential. We derived cell populations with properties of ectodermal and mesenchymal cells in two-dimensional culture and incorporated these divergent cell populations into three-dimensional (3D) epithelial tissues. When grown in specific media and substrate… CONTINUE READING

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