Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation

Abstract

Antigen-loaded dendritic cells (DC) are capable of priming naïve T cells and therefore represent an attractive adjuvant for vaccine development in anti-tumor immunotherapy. Numerous protocols have been described to date using different maturation cocktails and time periods for the induction of mature DC (mDC) in vitro. For clinical application, the use of… (More)
DOI: 10.1186/1479-5876-8-90

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