Three column intermittent simulated moving bed chromatography: 1. Process description and comparative assessment.

@article{Jermann2014ThreeCI,
  title={Three column intermittent simulated moving bed chromatography: 1. Process description and comparative assessment.},
  author={Simon Jermann and Marco Mazzotti},
  journal={Journal of chromatography. A},
  year={2014},
  volume={1361},
  pages={125-38}
}
The three column intermittent simulated moving bed (3C-ISMB) process is a new type of multi-column chromatographic process for binary separations and can be regarded as a modification of the I-SMB process commercialized by Nippon Rensui Corporation. In contrast to conventional I-SMB, this enables the use of only three instead of four columns without compromising product purity and throughput. The novel mode of operation is characterized by intermittent feeding and product withdrawal as well as… CONTINUE READING