Three chemokines with potential functions in T lymphocyte-independent and -dependent B lymphocyte stimulation.

@article{Schaniel1999ThreeCW,
  title={Three chemokines with potential functions in T lymphocyte-independent and -dependent B lymphocyte stimulation.},
  author={Christoph Schaniel and Federica Sallusto and Christiane Ruedl and Paschalis Sideras and Fritz Georg Melchers and Antonius G. Rolink},
  journal={European journal of immunology},
  year={1999},
  volume={29 9},
  pages={2934-47}
}
Three clustered mouse chemokine genes, ABCD-1, -2 and -3, are all expressed highly in dendritic cells and, at various levels, in activated B cells. T cell-independently activated B cells express ABCD-1 and -2, but not -3. T cell-dependently activated B cells express all three. ABCD-1 attracts activated CD8+ cytotoxic T cells and CD4+ helper T cells of type 1 and 2. ABCD-2 preferentially attracts type 2 helper T cells, while ABCD-3 does not attract T cells at all. Both ABCD-1 and ABCD-2 bind to… CONTINUE READING