Three cases of suspected sugammadex-induced hypersensitivity reactions.

@article{Godai2012ThreeCO,
  title={Three cases of suspected sugammadex-induced hypersensitivity reactions.},
  author={Kohei Godai and Maiko Hasegawa-Moriyama and Tamotsu Kuniyoshi and T Kakoi and Kazuya Ikoma and Sumikazu Isowaki and Atsushi Matsunaga and Yuichi Kanmura},
  journal={British journal of anaesthesia},
  year={2012},
  volume={109 2},
  pages={216-8}
}
Neuromuscular blocking agents have been implicated in 60-70% of anaphylactic events associated with anaesthesia. We report two cases of probable hypersensitivity reaction to sugammadex and an additional suspected but less supported case of possible immune-mediated reaction or other adverse reaction. The patients were given a bolus of sugammadex 100 mg immediately before extubation. In all three patients, a possible allergic reaction was suspected within 4 min of sugammadex administration, but… CONTINUE READING

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