Three- and four-year cognitive outcome in children with noncortical brain tumors treated with whole-brain radiotherapy.

@article{Radcliffe1992ThreeAF,
  title={Three- and four-year cognitive outcome in children with noncortical brain tumors treated with whole-brain radiotherapy.},
  author={Jerilynn Radcliffe and Roger J. Packer and Tina Atkins and Greta R. Bunin and Lawrence Schut and Joel W. Goldwein and Leslie N. Sutton},
  journal={Annals of neurology},
  year={1992},
  volume={32 4},
  pages={551-4}
}
Cognitive function and school achievement were studied prospectively over 3 to 4 years in 19 children treated for brain tumors with whole-brain radiotherapy; 14 of 19 also received adjuvant chemotherapy. For the group as a whole, mean IQ fell from a baseline of 104 to 92 at follow-up (p < 0.01). Age was inversely correlated with change in IQ over time (r = 0.71; p < 0.001). Children younger than 7 years at diagnosis had a mean IQ loss of 27 points, while children over 7 years at diagnosis… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Helping survivors of medulloblastoma learn from what we learn.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2013

Similar Papers

Loading similar papers…