Three-Step Model for Polarized Sorting of KIF17 into Dendrites

@article{Franker2016ThreeStepMF,
  title={Three-Step Model for Polarized Sorting of KIF17 into Dendrites},
  author={M. Franker and M. R. Silva and R. Tas and Elena Tortosa and Yujie Cao and C. P. Frias and A. F. Janssen and Phebe S. Wulf and L. Kapitein and C. Hoogenraad},
  journal={Current Biology},
  year={2016},
  volume={26},
  pages={1705-1712}
}
  • M. Franker, M. R. Silva, +7 authors C. Hoogenraad
  • Published 2016
  • Biology, Medicine
  • Current Biology
    • Kinesin and dynein motors drive bidirectional cargo transport along microtubules and have a critical role in polarized cargo trafficking in neurons [1, 2]. The kinesin-2 family protein KIF17 is a dendrite-specific motor protein and has been shown to interact with several dendritic cargoes [3-7]. However, the mechanism underlying the dendritic targeting of KIF17 remains poorly understood [8-11]. Using live-cell imaging combined with inducible trafficking assays to directly probe KIF17 motor… CONTINUE READING
    View on Elsevier
    cell.com
    16 Citations
    Background Citations
    5
    16 Citations
    Citation Type

    Citation Type

    A novel strategy to visualize vesicle‐bound kinesins reveals the diversity of kinesin‐mediated transport
    • 4
    Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory
    • 6
    • PDF
    Structure and Function of an Actin-Based Filter in the Proximal Axon.
    • 16
    Local mechanisms regulating selective cargo entry and long-range trafficking in axons
    • 20
    Spatial control of membrane traffic in neuronal dendrites
    • 2
    TRIM46 Organizes Microtubule Fasciculation in the Axon Initial Segment
    • 7
    • PDF
    The functional architecture of axonal actin
    • 25
    • PDF
    Rab23/Kif17 regulate meiotic progression in oocytes by modulating tubulin acetylation and actin dynamics
    • 6
    • PDF
    Polarized trafficking: the palmitoylation cycle distributes cytoplasmic proteins to distinct neuronal compartments.
    • 18
    The impact of cytoskeletal organization on the local regulation of neuronal transport
    • 46

    References

    SHOWING 1-10 OF 31 REFERENCES
    Mixed Microtubules Steer Dynein-Driven Cargo Transport into Dendrites
    • 256
    A Role for Kif17 in Transport of Kv4.2*
    • 88
    • PDF
    A Selective Filter for Cytoplasmic Transport at the Axon Initial Segment
    • 283
    • PDF
    The Translocation Selectivity of the Kinesins that Mediate Neuronal Organelle Transport
    • 66
    Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head
    • 290
    • PDF
    Selective Microtubule-Based Transport of Dendritic Membrane Proteins Arises in Concert with Axon Specification
    • 69
    • PDF
    Which way to go? Cytoskeletal organization and polarized transport in neurons
    • 187
    Probing intracellular motor protein activity using an inducible cargo trafficking assay.
    • 121
    • PDF
    Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes
    • 291
    • PDF
    Two binding partners cooperate to activate the molecular motor Kinesin-1
    • 195
    • PDF