Three Myosins Contribute Uniquely to the Assembly and Constriction of the Fission Yeast Cytokinetic Contractile Ring

@article{Laplante2015ThreeMC,
  title={Three Myosins Contribute Uniquely to the Assembly and Constriction of the Fission Yeast Cytokinetic Contractile Ring},
  author={Caroline Laplante and Julien Berro and Erdem Karatekin and Ariel Hernandez-Leyva and Rachel Lee and Thomas D. Pollard},
  journal={Current Biology},
  year={2015},
  volume={25},
  pages={1955-1965}
}
Cytokinesis in fission yeast cells depends on conventional myosin-II (Myo2) to assemble and constrict a contractile ring of actin filaments. Less is known about the functions of an unconventional myosin-II (Myp2) and a myosin-V (Myo51) that are also present in the contractile ring. Myo2 appears in cytokinetic nodes around the equator 10 min before spindle pole body separation (cell-cycle time, -10 min) independent of actin filaments, followed by Myo51 at time zero and Myp2 at time +20 min, both… CONTINUE READING
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