Three Distinct Condensin Complexes Control C. elegans Chromosome Dynamics

  title={Three Distinct Condensin Complexes Control C. elegans Chromosome Dynamics},
  author={Gyorgyi Csankovszki and Karishma S. Collette and Karin Spahl and James R. Carey and Martha A Snyder and Emily Petty and Uchita Patel and Tomoko M. Tabuchi and Hongbin Liu and I. McLeod and James Thompson and Ali Sarkeshik and John Yates and Barbara Ann Meyer and Kirsten Hagstrom},
  journal={Current Biology},
BACKGROUND Condensin complexes organize chromosome structure and facilitate chromosome segregation. Higher eukaryotes have two complexes, condensin I and condensin II, each essential for chromosome segregation. The nematode Caenorhabditis elegans was considered an exception, because it has a mitotic condensin II complex but appeared to lack mitotic condensin I. Instead, its condensin I-like complex (here called condensin I(DC)) dampens gene expression along hermaphrodite X chromosomes during… CONTINUE READING
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