Three-Dimensional Reflectance Traction Microscopy.

  title={Three-Dimensional Reflectance Traction Microscopy.},
  author={Jihan Kim and Christopher Allen Rucksack Jones and Nicholas Scott Groves and Bo Sun},
  journal={PloS one},
  volume={11 6},
Cells in three-dimensional (3D) environments exhibit very different biochemical and biophysical phenotypes compared to the behavior of cells in two-dimensional (2D) environments. As an important biomechanical measurement, 2D traction force microscopy can not be directly extended into 3D cases. In order to quantitatively characterize the contraction field, we have developed 3D reflectance traction microscopy which combines confocal reflection imaging and partial volume correlation postprocessing… CONTINUE READING
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