Three-Dimensional Reconstruction of Brain-wide Wiring Networks in Drosophila at Single-Cell Resolution

@article{Chiang2011ThreeDimensionalRO,
  title={Three-Dimensional Reconstruction of Brain-wide Wiring Networks in Drosophila at Single-Cell Resolution},
  author={A. Chiang and Chih-Yung Lin and Chao-Chun Chuang and Hsiu-Ming Chang and C. Hsieh and Chang-Wei Yeh and C. Shih and Jian-Jheng Wu and Guo-Tzau Wang and Y. Chen and Cheng-Chi Wu and G. Chen and Y. Ching and Ping-Chang Lee and Chih-Yang Lin and Hui-Hao Lin and C. Wu and Hao-Wei Hsu and Yun-An Huang and Jing-Yi Chen and Hsin-Jung Chiang and Chun-Fang Lu and Ru-Fen Ni and C. Yeh and Jenn-Kang Hwang},
  journal={Current Biology},
  year={2011},
  volume={21},
  pages={1-11}
}
BACKGROUND Animal behavior is governed by the activity of interconnected brain circuits. Comprehensive brain wiring maps are thus needed in order to formulate hypotheses about information flow and also to guide genetic manipulations aimed at understanding how genes and circuits orchestrate complex behaviors. RESULTS To assemble this map, we deconstructed the adult Drosophila brain into approximately 16,000 single neurons and reconstructed them into a common standardized framework to produce a… Expand
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