Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market

  title={Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market},
  author={Asuka Kaizaki-Mitsumoto and Naoki Noguchi and Saki Yamaguchi and Yuki Odanaka and Satoko Matsubayashi and Hiroki Kumamoto and Kiyoshi Fukuhara and Masahiko Funada and Kiyoshi Wada and Satoshi Numazawa},
  journal={Forensic Toxicology},
Twenty-two samples of ingredients of recreational drugs before being sold on the drug market obtained from a dubious drug dealer were analyzed by gas chromatography/mass spectrometry, high-resolution mass spectrometry, and nuclear magnetic resonance (NMR) spectroscopy. The present study showed 15 novel designer drugs, which have not been described in scientific literature. They included three NBOMe drugs 25H-NBOMe, 25D-NBOMe, and 25E-NBOMe, three other phenethylamine-type drugs 25I-NBMD, RH34… 

25I-NBOME (2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine)-A HARMFUL HALLUCINOGEN REVIEW.

The growing number of fatal and non-fatal intoxication cases indicates that 25I-NBOMe should be considered as a serious danger to public health.

Tentative identification of the phase I and II metabolites of two synthetic cathinones, MDPHP and α-PBP, in human urine.

Using liquid chromatography-high resolution mass spectrometry, the metabolites of two pyrrolidine cathinone derivatives, α-PBP and the less common MDPHP were tentatively identified in urine samples collected from patients admitted to hospital following drug intoxications.

Identification of five pyrrolidinyl substituted cathinones and the collision-induced dissociation of electrospray-generated pyrrolidinyl substituted cathinones.

The analytical properties of five pyrrolidinyl substituted cathinones are reported on, in order to study the collision-induced dissociation (CID) characteristic fragmentation routes of pyrroldinononaphenone and β-THNPH, for the first time.

Identification of 1‐(2,3‐dihydro‐1H‐inden‐5‐yl)‐2‐(ethylamino)pentan‐1‐one (bk‐IVP) in a Seized Drug Exhibit

Features of spectra and chemical tests are reported that distinguish this class of cathinones from heterocyclic analogs that evade regulation and obscuring their identities in routine analyses.

1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances.

Two structurally distinct classes that have appeared as dissociative-based new psychoactive substances (NPS) are the 1,2-diarylethylamines and β-keto-arylcyclohexylamines.

Comparison of the behavioral effects of mescaline analogs using the head twitch response in mice

The head twitch response (HTR), a 5-HT2A receptor-mediated behavior induced by serotonergic hallucinogens, was used to assess the effects of mescaline and several analogs in C57BL/6J mice, and the potency relationships for these compounds in mice closely parallel the human hallucinogenic data.

The analysis of illicit 25X-NBOMe seizures in Western Australia.

The quantitation of three different NBOMe compounds, 25C-NBOMe, 25I-NBome and 25B-NB OMe in seizures by Western Australia Police of blotter papers and tablets are reported.

Interpol review of controlled substances 2016–2019☆



Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products

Two new types of synthetic cannabinoids, an AM-2201 benzimidazole analog (FUBIMINA, 1) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM, 2), and three newly emerged

Identification and quantitation of 5-fluoro-ADB, one of the most dangerous synthetic cannabinoids, in the stomach contents and solid tissues of a human cadaver and in some herbal products

To the authors' knowledge, this is the first reported identification and quantitation of 5-fluoro-ADB in human specimens and herbal products.

Determination of γ-hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS.

Identification and quantitation of 5-fluoro-ADB-PINACA and MAB-CHMINACA in dubious herbal products

Police officials brought three different packages of herbal blends, with brand names “AL 37”, “AP 31”, and “GM sapphire”, to our laboratory for drug testing. Using our in-house high-resolution mass

Phenomenon of new drugs on the Internet: the case of ketamine derivative methoxetamine

The online availability of information on novel psychoactive drugs, such as methoxethanine, may constitute a pressing public health challenge and better international collaboration levels and novel forms of intervention are necessary to tackle this fast‐growing phenomenon.

The forefront of drug abuse—recent trends in illegal drug markets in Japan

  • 2013