Three - Dimensional Structure of Phoratoxin in Solution : Combined Use of Nuclear Magnetic Resonance , Distance Geometry , and Restrained Molecular Dynamics ?

The solution conformation of phoratoxin, a 46-residue plant protein, has been investigated by 'H nuclear magnetic resonance ( N M R ) spectroscopy. The spectrum is assigned in a sequential manner by a combination of two-dimensional N M R techniques to demonstrate through-bond and through-space (<5 A) connectivities. A set of 331 approximate interproton… (More)