Thoracic but not lumbar epidural anaesthesia increases liver blood flow after major abdominal surgery.

@article{Kortgen2009ThoracicBN,
  title={Thoracic but not lumbar epidural anaesthesia increases liver blood flow after major abdominal surgery.},
  author={Andreas Kortgen and Malte Silomon and Christine Pape-Becker and Heiko Buchinger and Ulrich Grundmann and Michael Bauer},
  journal={European journal of anaesthesiology},
  year={2009},
  volume={26 2},
  pages={111-6}
}
BACKGROUND AND OBJECTIVE Epidural blockade in major abdominal surgery bears the potential to increase gastrointestinal perfusion and thus to improve patient outcome. The aim of this study was to assess the differential influence of thoracic and lumbar epidural anaesthesia and analgesia (EAA) on blood lactate levels and central venous oxygen saturation (ScvO2) as parameters of global oxygen supply/demand ratio, as well as on the plasma disappearance rate of indocyanine green (PDR(ICG)), a… CONTINUE READING

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Subsequently , epidural application of local anaesthetics was started with a bolus of bupivacaine 0.25% ( thoracic 10 ml , lumbar 12 ml ) followed by continuous infusion of bupivacaine ( thoracic 8 ml h(-1 ) 0.175% , lumbar 10 ml h(-1 ) 0.125% ) and fentanyl ( 2 microg ml(-1 ) ) .
Subsequently , epidural application of local anaesthetics was started with a bolus of bupivacaine 0.25% ( thoracic 10 ml , lumbar 12 ml ) followed by continuous infusion of bupivacaine ( thoracic 8 ml h(-1 ) 0.175% , lumbar 10 ml h(-1 ) 0.125% ) and fentanyl ( 2 microg ml(-1 ) ) .
The aim of this study was to assess the differential influence of thoracic and lumbar epidural anaesthesia and analgesia ( EAA ) on blood lactate levels and central venous oxygen saturation ( ScvO2 ) as parameters of global oxygen supply / demand ratio , as well as on the plasma disappearance rate of indocyanine green ( PDR(ICG ) ) , a noninvasive method to evaluate liver perfusion .
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