This information is current as T Lymphocytes Migration in Chemokine-Stimulated Human L-Plastin Regulates Polarization and

Chemokines such as SDF-1a play a crucial role in orchestrating T lymphocyte polarity and migration via polymerization and reorganization of the F-actin cytoskeleton, but the role of actin-associated proteins in this process is not well characterized. In this study, we have investigated a role for L-plastin, a leukocyte-specific F-actin–bundling protein, in… (More)