Thirty-one autopsy cases of trisomy 18: clinical features and pathological findings.

@article{Kinoshita1989ThirtyoneAC,
  title={Thirty-one autopsy cases of trisomy 18: clinical features and pathological findings.},
  author={Masanobu Kinoshita and Yaeko Nakamura and Ryousuke Nakano and Mitsunori Morimatsu and Shigeo Fukuda and Y. Nishimi and Tatsuo Hashimoto},
  journal={Pediatric pathology},
  year={1989},
  volume={9 4},
  pages={
          445-57
        }
}
The clinical features and morphological findings in 31 Japanese infants with trisomy 18 are presented. The majority were small-for-date infants. There was no sex predominance in our series, as opposed to male:female ratios of 1:3 reported in the literature. The average age at death was greater in females than in males. Cardiovascular anomalies were consistently present; ventricular septar defect and patent ductus arteriosus being the most common malformations. Various other internal… CONTINUE READING

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