Thirty-month follow-up of sub-optimal responders to multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana.

@article{Awadzi2004ThirtymonthFO,
  title={Thirty-month follow-up of sub-optimal responders to multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana.},
  author={Kwablah Awadzi and Simon Kwaku Attah and E T Addy and Nicholas O. Opoku and Benjamin Quartey and Janis K. Lazdins-Helds and Kamruddin Ahmed and Boakye A. Boatin and Daniel Adjei Boakye and Geoffrey Edwards},
  journal={Annals of tropical medicine and parasitology},
  year={2004},
  volume={98 4},
  pages={359-70}
}
The pathogenesis of the sub-optimal response of Onchocerca volvulus to ivermectin was investigated in a 30-month follow-up of 28 individuals who, in a previous study, had been found to show a sub-optimal (N = 15) or adequate response (N = 13) to multiple treatments with the drug. Verbal informed consent was obtained before each subject was given a general clinical and ocular examination. Skin snips were taken from both iliac crests and both calves. Seventeen nodule carriers were hospitalized… CONTINUE READING

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