• Chemistry
  • Published 1981

Thirteen Week Oral (Diet) Toxicity Study of Trinitrotoluene (TNT), Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) and TNT/RDX Mixtures in the Fischer 344 Rat

@inproceedings{Levine1981ThirteenWO,
  title={Thirteen Week Oral (Diet) Toxicity Study of Trinitrotoluene (TNT), Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) and TNT/RDX Mixtures in the Fischer 344 Rat},
  author={Barry S. Levine and E M Furedi and Donovan E. Gordon and John M. Burns and Paul M Lish},
  year={1981}
}
Abstract : This study was conducted to evaluate the toxicity of the munitions compounds 2,4,6-trinitrotoluene (TNT; CAS Reg. No. 118-96-7) and hexahydro-1,3, 5-trinitro-1,3,5-triazine (RDX; CAS Reg. No. 121-82-4), and their potential toxic interactions in Fischer 344 rats when administered in the diet for at least 13 weeks. The data derived were also to be used to select dose levels for comprehensive chronic toxicity/carcinogenicity studies. Groups of 10 rats per sex received TNT at doses of 1… CONTINUE READING

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