Third-generation cephalosporins for polymicrobial surgical sepsis.

  title={Third-generation cephalosporins for polymicrobial surgical sepsis.},
  author={Hunter H. Stone and Priscilla R. Strom and Timothy C. Fabian and W E Dunlop},
  journal={Archives of surgery},
  volume={118 2},
During 31 months of study, 808 patients with polymicrobial surgical infection were randomized for antibiotic therapy between a third-generation cephalosporin (moxalactam disodium [149], cefotaxime sodium [125], and cefoperazone sodium [141]) and the combination of gentamicin sulfate plus clindamycin (393). Results based on antibiotic therapy included the… CONTINUE READING