Thiourea-catalyzed Diels–Alder reaction of a naphthoquinone monoketal dienophile

Abstract

A variety of organocatalysts were screened for the catalysis of the naphthoquinone monoketal Diels-Alder reaction. In this study we found that Schreiner's thiourea catalyst 10 and Jacobson's thiourea catalyst 12 facilitate the cycloaddition of the sterically hindered naphthoquinone monoketal dienophile 3 with diene 4. The use of thiourea catalysis allowed… (More)
DOI: 10.3762/bjoc.9.158

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@inproceedings{Kramer2013ThioureacatalyzedDR, title={Thiourea-catalyzed Diels–Alder reaction of a naphthoquinone monoketal dienophile}, author={Carsten S Kramer and Stefan Br{\"a}se}, booktitle={Beilstein journal of organic chemistry}, year={2013} }