Thiostrepton inhibition of tRNA delivery to the ribosome.

  title={Thiostrepton inhibition of tRNA delivery to the ribosome.},
  author={Rub{\'e}n Camilo Lois Gonz{\'a}lez and Steven Chu and Joseph D. Puglisi},
  volume={13 12},
Ribosome-stimulated hydrolysis of guanosine-5'-triphosphate (GTP) by guanosine triphosphatase (GTPase) translation factors drives protein synthesis by the ribosome. Allosteric coupling of GTP hydrolysis by elongation factor Tu (EF-Tu) at the ribosomal GTPase center to messenger RNA (mRNA) codon:aminoacyl-transfer RNA (aa-tRNA) anticodon recognition at the… CONTINUE READING
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