Thioredoxin-1 and endothelial cell aging: role in cardiovascular diseases.

@article{Altschmied2009Thioredoxin1AE,
  title={Thioredoxin-1 and endothelial cell aging: role in cardiovascular diseases.},
  author={Joachim Altschmied and Judith Haendeler},
  journal={Antioxidants & redox signaling},
  year={2009},
  volume={11 7},
  pages={1733-40}
}
The thioredoxin-1 (Trx-1) system consists of two oxidoreductases, thioredoxin reductase and Trx-1. Trx-1 is a ubiquitously expressed oxidoreductase. The cellular functions of Trx-1 are wide range. They include protein disulfide reduction, DNA synthesis, protection from apoptosis, redox regulation of a variety of proteins, transcription factors and reduction… CONTINUE READING