Corpus ID: 1484650

Thiomersal-containing vaccines - a review of the current state of knowledge.

@article{Goos2015ThiomersalcontainingV,
  title={Thiomersal-containing vaccines - a review of the current state of knowledge.},
  author={Aleksandra Gołos and Anna Lutyńska},
  journal={Przeglad epidemiologiczny},
  year={2015},
  volume={69 1},
  pages={
          59-64, 157-61
        }
}
Thiomersal is an organomercury compound known for its antiseptic and antifungal properties and used as an antibacterial agent in pharmaceutical products, including vaccines and other injectable biological products. In recent years, concerns about the possible link between immunization with thiomersal-containing vaccines and autism development have grown. Many case-control and cohort studies have been conducted on a number of populations, and none of them have confirmed the hypothetical relation… Expand
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References

SHOWING 1-10 OF 25 REFERENCES
The evidence for the safety of thiomersal in newborn and infant vaccines.
TLDR
The scientific evidence is not yet sufficiently strong to provide the same level of assurance for thiomersal-containing vaccines for use in pregnant women or the premature or low birth weight infant. Expand
Mercury concentrations and metabolism in infants receiving vaccines containing thiomersal: a descriptive study
TLDR
Administration of vaccines containing thiomersal does not seem to raise blood concentrations of mercury above safe values in infants, and ethylmercury seems to be eliminated from blood rapidly via the stools after parenteral administration of th iomersal in vaccines. Expand
Autism and thimerosal-containing vaccines: lack of consistent evidence for an association.
TLDR
The body of existing data, including the ecologic data presented herein, is not consistent with the hypothesis that increased exposure to Thimerosal-containing vaccines is responsible for the apparent increase in the rates of autism in young children being observed worldwide. Expand
An assessment of thimerosal use in childhood vaccines.
TLDR
No evidence of harm caused by doses of thimerosal in vaccines, except for local hypersensitivity reactions is revealed, however, some infants may be exposed to cumulative levels of mercury during the first 6 months of life that exceed EPA recommendations. Expand
Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases.
TLDR
No consistent significant associations were found between TCVs and neuro developmental outcomes and studies with uniform neurodevelopmental assessments of children with a range of cumulative thimerosal exposures are needed. Expand
Thimerosal-containing vaccines and autism: a review of recent epidemiologic studies.
TLDR
Recent pharmacokinetic and epidemiologic studies published between 2003 and 2008 regarding the proposed link between thimerosal and autism are reviewed. Expand
Global Vaccination Recommendations and Thimerosal
TLDR
Thimerosal has been used as a preservative in vaccines to prevent contamination of multidose vials from bacteria and fungi since the 1930s and is one of the most effective ways to prevent infectious disease and deaths globally. Expand
Prenatal and Infant Exposure to Thimerosal From Vaccines and Immunoglobulins and Risk of Autism
TLDR
In the study of MCO members, prenatal and early-life exposure to ethylmercury from thimerosal-containing vaccines and immunoglobulin preparations was not related to increased risk of ASDs. Expand
Thimerosal-Containing Vaccines and Autistic Spectrum Disorder: A Critical Review of Published Original Data
TLDR
Evidence does not support a change in the standard of practice with regard to administration of thimerosal-containing vaccines in areas of the world where they are used, and the pharmacokinetics of ethylmercury make such an association less likely. Expand
Thimerosal-Containing Vaccines and Autistic Spectrum Disorder: A Critical Review of Published Original Data
TLDR
Evidence does not support a change in the standard of practice with regard to administration of thimerosal-containing vaccines in areas of the world where they are used, and the pharmacokinetics of ethylmercury make such an association less likely. Expand
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