Thiol proteases released in vitro by Fasciola hepatica.

  title={Thiol proteases released in vitro by Fasciola hepatica.},
  author={John Pius Dalton and Michelle Heffernan},
  journal={Molecular and biochemical parasitology},
  volume={35 2},
Immature Fasciola hepatica release 11 distinct proteases when cultured in vitro for 16 h as revealed by gelatin-substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Six of these proteases are active in the pH range 4.5 to 8.0. Five are acid proteases, being most active in the pH range 3.0 to 4.5. The majority of proteases released in vitro by immature flukes are also released by mature flukes; however, a 40-kDa protease released by immature flukes is a very minor… CONTINUE READING
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